A biomarker panel to discriminate between SIRS and sepsis and sepsis severity
نویسندگان
چکیده
منابع مشابه
A biomarker panel to discriminate between systemic inflammatory response syndrome and sepsis and sepsis severity
INTRODUCTION In this study, we report on initial efforts to discover putative biomarkers for differential diagnosis of a systemic inflammatory response syndrome (SIRS) versus sepsis; and different stages of sepsis. In addition, we also investigated whether there are proteins that can discriminate between patients who survived sepsis from those who did not. MATERIALS AND METHODS Our study grou...
متن کاملDefinition of Sepsis and Non-infectious SIRS
The word ‘‘sepsis’’ has its origins in the word ‘‘σήψις’’, which is the original Greek word for decomposition or putrefaction, and has been used in that context since before Hippocrates [1, 2]. However, although the word, sepsis, has been used for more than 2700 years, it is only relatively recently that we have begun to understand the pathophysiology of sepsis in any depth [3]. With this new i...
متن کاملSepsis as a model of SIRS.
Sepsis describes a complex clinical syndrome that results from the host inability to regulate the inflammatory response against infection. Despite more than 20 years of extensive study, sepsis and excessive systemic inflammatory response syndrome (SIRS) are still the leading cause of death in intensive care units. The clinical study of sepsis and new therapeutics remains challenging due to the ...
متن کاملSphingosine-1-phosphate is a novel biomarker in sepsis severity
Results All three groups of patients had significantly (P < 0.001) lower serum S1P concentrations than controls (median 457.9 μg/L; interquartile range, IQR 379.8-562.3 μg/L). The lowest S1P concentrations was found in the septic shock group (149.1 μg/L; IQR, 105.1-163.2 μg/L) compared to patients with severe sepsis (234.7 μg/L; IQR, 185.4-342.6 μg/L) and sepsis (246.7 μg/L; IQR, 201.7306.0 μg/...
متن کاملKnowledge and recognition of SIRS and sepsis among pediatric nurses.
BACKGROUND A large amount of research demonstrates the importance of key interventions in reducing mortality rates of pediatric patients with sepsis (Dellinger et al., 2008). Assessment and recognition of declining status must occur for interventions to be initiated. Of health care practitioners, nurses typically spend the most time with patients, and they must be knowledgeable in recognizing t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Emergencies, Trauma, and Shock
سال: 2010
ISSN: 0974-2700
DOI: 10.4103/0974-2700.58666